: a constitutional predisposition toward a particular state or condition and especially one that is abnormal or diseased diathesis [di-ath´ĕ-sis] an unusual constitutional susceptibility or predisposition to a particular disease. adj., adj diathet´ic. di·ath·e·sis (dī-ath'ĕ-sis. The diathesis–stress model is a psychological theory that attempts to explain behavior as a predispositional vulnerability together with stress from life experiences. Bleeding diathesis; Classification and external resources; Specialty: hematology: ICD-10: D69.9: ICD-9-CM: 287.9: DiseasesDB: 1442: MeSH: D006474 Depression information and bipolar disorder information by John McManamy. Psychology definition for Diathesis-Stress Theory in normal everyday language, edited by psychologists, professors and leading students. Help us get better. Treating bipolar disorder. Treatment for bipolar disorder aims to reduce the number and severity of the episodes of depression and mania that characterise the condition. Soft Bipolar Spectrum - Hyperthymia. By, Ivan Goldberg, M.D. 1: Am J Psychiatry. 2005 Jan;162(1):137-45. Does sustained-release lithium reduce impulsive gambling and. Bipolar disorder can be devastating if not controlled. This article presents what researchers now consider to be the most likely causes of bipolar disorder. No one knows exactly what causes schizophrenia, and there are a number of existing theories seeking to explain the origins of the disease. The diathesis-stress theory.